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Showing posts with label Biotechnology. Show all posts
Showing posts with label Biotechnology. Show all posts

Knowing About Biological Safety Cabinet and What they Do?

Biological safety cabinet keeps workers safe and also sustaining quality. There is a requirement for regular certification. But what is the exact use of biological safety cabinets. This blog will provide info about the uses, working, and also the types of devices.

BSC’s, are ventilated enclosures in a lab. Within these, employees can handle dangerous specimens with safety. HEPA fan and filter units filter air away from people to direct harmful aerosols out of the cabinets. Furthermore, the fan/filter incessantly recirculates the air. Consequently, the cabinet has clean air. Eventually, the key purpose of a BSC is the safety of the people working in a lab. 

Class I

These protect employee and workspace in labs actively handling powders and chemicals. A front opening on every cabinet lets the clean air in. It moves with the help a built-in exhaust and HEPA filter before entering the unit. At the back side of the work surface, the air leaves the cabinet. The inward flow of the air controls the unsafe aerosols a people might generate within by directing them into filtration elements absorbing them.

Class II

These cabinets provide protection to the workspace, employees and the products present. The air enters the work area from a front aperture. The air inside continues under the work surface and travels up the back plenum. Next, most of the air recirculates through the main HEPA filter. This offers down flow, then the remaining air exits through another filter.

There are some features making it different from the class I cabinet. First, there is a front opening with specific, steady flow of the air inwards. Secondly, vertical, HEPA-filtered unidirectional airflow steadily moves through the key chamber. And thirdly, the exhaust air enters the adjacent laboratory through an external extraction system.

Class III

These are fully airtight enclosure with completely sealed front windows. This separates the employee from the unsafe specimen with a physical barrier, offering ideal protection. 

Workers wear long, heavy duty rubber gloves located on ports in the cabinet. These allow them to operate the product inside without compromising on containment.

For removing materials from the BSC, a side chamber has an airlock transfer hatch. Additionally, there might be a double door autoclave. Any materials removed from the cabinet goes through decontamination. Strict safety protocols are followed through every process, which has this kind of cabinet. This comprise putting on interlock for the doors and autoclave for ensuring that neither door is opened simultaneously as the other.

These are perfect for biosafety laboratories with ratings of 4. These labs have the deadliest biological agents. In these, employees abide by the highest containment and protection practices. Class III BSCs are among the methods in which BSL-4 labs work for protecting people and guarantee total containment.

Coming to a Conclusion 

Eventually, BSCs have a big role to play in maintaining the safety of the workers in the lab. So, it is always essential to check that the functioning of the same is very proper. 

The demand for these biological safety cabinet is on the rise because of the increase in the incidence of chronic diseases, and it will reach a value of USD 507.1 million by the end of this decade.

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How is Surging Population Driving Agricultural Biotechnology Market?

The world’s population has grown constantly since the age of human beings began; for example, in 1800 the population across the globe was under 1 billion, which has now, almost dramatically, risen to 7.7 billion. With this surging population, the need for enhancing the productivity of everything, for catering to the requirements of the people, has increased as well. This includes the productivity in agricultural fields, of course. In the old days, the only concern of people was to somehow grow enough food for their survival, and while survival is the major concern today as well, the priorities of the human race seem to have shifted.

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Farming used to be the primary occupation in the past, but since the advent of industries and machines, the agricultural sector has somewhat been neglected. At the present time, however, there is a pressing need for increasing the agricultural productivity, which is why a number of technological advancements have occurred in the agricultural sector. One of such developments is the emergence of agricultural biotechnology, which involves the utilization of science for modifying animals and plants. This is done to breed out undesirable characteristics, such as low productivity and susceptibility to diseases. Furthermore, any beneficial traits can be bred in by making use of a gene which contains the specific characteristic.


Agricultural biotechnology helps in enhancing agricultural productivity and animal feeds, for increasing their nutrient intake and reducing environmental waste. Attributed to such positive aspects, the agricultural biotechnology market is expected to advance at a substantial rate in the coming years. The different technologies utilized in agricultural biotechnology are biochips, genome editing tools, synthetic biology, deoxyribonucleic acid (DNA) sequencing, and ribonucleic acid interference (RNAi). Out of these, genomic editing tools are used the most, primarily in agricultural research.

Hence, agricultural biotechnology is increasingly being adopted for increasing the agricultural productivity
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Next-Generation Sequencing Market Size Will Make a Huge Impact in Near Future

The global next-generation sequencing market is growing significantly due to advances in next-generation technologies, increasing scientists and researchers’ compliance for next-generation sequencing, and low cost of next-generation sequencing methods compared to conventional sequencing methods in the industry. The unexplored next-generation sequencing market in emerging economies and increasing focus for the development of personalized medicine are creating opportunities for the global next-generation sequencing market to grow at a considerable rate in the coming years.

The advanced research and development activities by the major players are propelling the demand for cost effective and efficient next-generation sequencing platforms. However, interpretation of large volume of complex sequencing data through next-generation sequencing platforms is a major challenge in global next-generation sequencing market.


The global next-generation sequencing market is categorized as technology type, sequencing workflow, applications, and end-users. Based on technology type, the next-generation sequencing market is categorized as pyrosequencing, ion-semiconductor sequencing, sequencing by synthesis, single molecule realtime sequencing, and sequencing by ligation. The sequencing by synthesis segment leads the global next-generation sequencing market. Based on sequencing workflow, the next-generation sequencing market is categorized as next-generation pre-sequencing, next-generation sequencing platforms, and next-generation sequencing services.

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Based on applications, the next-generation sequencing market can be categorized as diagnostics, drug discovery, animal and agriculture research, personalized medicine, and others. End-users of next-generation sequencing include academic and research institutes, biopharmaceutical and biotechnology companies, hospitals, and others. Academic and research institutes lead the global next-generation sequencing market.

Some of the major players operating in the global next-generation sequencing market are Agilent Technologies, Inc., F. Hoffmann-La Roche AG, Biomatters, Ltd., GATC Biotech AG, Illumina, Inc., Thermo Fisher Scientific, Inc., Pacific Biosciences, Oxford Nanopore Technologies, Ltd, Macrogen, Inc. among others.
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